I don't know if I really have a top 5 list, but since people love lists, here are a couple:
Games shown at E3 with game play footage that I'm most interested in:
Fallout 4
XCom 2
No Man's Sky
Deus Ex: Mankind Divided
Ashen (Could use a bit more game play, but I'll take it)
Games shown at E3 with cinematic trailers, that I would like to know more about:
Mirror's Edge: Catalyst
Mass Effect: Andromeda
Dishonored 2
Final Fantasy VII Remake
Games that I might like if I had a console box:
Rare Replay
Horizon: Zero Dawn (I was more interested in this before I started writing this post, because the setting is basically Enslaved: Odyssey to the West, but after re-watching the trailer, it looks like yet another AAA action game that mixes stealth, crafting, and pretentious cut scenes. Sigh. (And as I complained about during my press conference post, there is absolutely no need for the protagonist to narrate every. Damn. Thing.)
Genre that we've seen more than enough of by now:
Resource gathering/survival games (You would think I would like them because LOL exploration, but jesuschrist these games are no fun at all)
For better or for worse:
The majority of the games I'm interested in are sequels/re-releases. Shame on me or shame on developers?